iPSC Lines - Detail

Designation
PiZZ100-MM
Alias
100-3-Cr1-MM56
Description
bi-allelic CRISPR correction of Z mutation
Species Cell Type Disease Ethnicity Race Secondary Race Karyotype Age Parent Avail
Human IPSC Alpha-1 antitrypsin deficiency Not Hisp/Lat White 46XX 67 PiZZ100 Yes


 
Institution Boston University
Passage Number 41
Starting Materials None Reported
Culture Platform mTeSR adapted
IPSC Reprogramming Method EF1a-hSTEMCCA4 loxp lentiviral infection
 
 
 
 
Description Parent Reporter Reporter Type Reporter Technique Knockout Gene Correction Other Text
bi-allelic CRISPR correction of Z mutation PiZZ100 No No Yes - Homozygous CRISPR-Cas9 editing with DNA oligo repair template