iPSC Lines - Detail

Designation
PiZZ6-MM
Alias
PIZZ6S-3-MM2
Description
bi-allelic CRISPR correction of SERPINA1 Z mutation
Species Cell Type Disease Ethnicity Race Secondary Race Karyotype Age Parent Avail
Human IPSC Alpha-1 antitrypsin deficiency Not Hisp/Lat White 46XX 16 PiZZ6 Yes


 
Institution Boston University
Passage Number 33
Starting Materials None Reported
Culture Platform mTeSR adapted
IPSC Reprogramming Method Sendai Virus
 
 
 
 
File Name Document Type
PIZZ6-S3-MM2 KT(1).pdf Karyotype
PiZZ6-S3-MM2 KT(2).pdf Karyotype
PiZZ6S-3-M2 STR.pdf STR Analysis
 
 
Description Parent Reporter Reporter Type Reporter Technique Knockout Gene Correction Other Text
bi-allelic CRISPR correction of SERPINA1 Z mutation PiZZ6 No No Yes - Homozygous CRISPR-Cas9 editing with DNA oligo repair template