iPSC Lines - Detail

Designation
PiZZ6-MZ
Alias
PiZZ6S-3-MZ13
Description
mono-allelic CRISPR correction of SERPINA1 Z mutation
Species Cell Type Disease Ethnicity Race Secondary Race Karyotype Age Parent Avail
Human IPSC Alpha-1 antitrypsin deficiency Not Hisp/Lat White 46XX 16 PiZZ6 Yes


 
Institution Boston University
Passage Number
Starting Materials PBMCs
Culture Platform mTeSR adapted
IPSC Reprogramming Method Sendai Virus
 
 
 
 
File Name Document Type
PiZZ6-S3-MZ13 KT(1).pdf Karyotype
PiZZ6-S3-MZ13 KT(2).pdf Karyotype
 
 
Description Parent Reporter Reporter Type Reporter Technique Knockout Gene Correction Other Text
mono-allelic CRISPR correction of SERPINA1 Z mutation PiZZ6 No No Yes - Heterozygous CRISPR-Cas9 editing with DNA oligo repair template