iPSC Lines - Detail

Designation
PiZZ100-MZ
Alias
100-3-Cr1-MZ58
Description
mono-allelic CRISPR correction of Z mutation
Species Cell Type Disease Ethnicity Race Secondary Race Karyotype Age Parent Avail
Human IPSC Alpha-1 antitrypsin deficiency Not Hisp/Lat White 46XX 67 PiZZ100 Yes


 
Institution Boston University
Passage Number 51
Starting Materials None Reported
Culture Platform mTeSR adapted
IPSC Reprogramming Method EF1a-hSTEMCCA4 loxp lentiviral infection
 
 
 
 
File Name Document Type
100-3-Cr1-MZ58 KT.pdf Karyotype
REPORT CLG-27051.pdf Karyotype
 
 
Description Parent Reporter Reporter Type Reporter Technique Knockout Gene Correction Other Text
mono-allelic CRISPR correction of Z mutation PiZZ100 No No Yes - Heterozygous CRISPR-Cas9 editing with DNA oligo repair template