iPSC Lines - Detail

Designation
PiZZ1 MM
Alias
PiZZ1-1-Cr4-MM1
Description
bi-allelic CRISPR correction of Z mutation
Species Cell Type Disease Ethnicity Race Karyotype Age Parent Avail
Human IPSC Alpha-1 antitrypsin deficiency None Reported None Reported 46XY 44 PiZZ1 Yes


 
Institution Boston University
Passage Number 59
Starting Materials None Reported
Culture Platform mTeSR adapted
IPSC Reprogramming Method EF1a-hSTEMCCA4 loxp lentiviral infection
 
 
 
 
File Name Document Type
PiZZ1 MM KT.pdf Karyotype
PiZZ1 MM STR.pdf STR Analysis
 
 
Description Parent Reporter Reporter Type Reporter Technique Knockout Gene Correction Other Text
bi-allelic CRISPR correction of Z mutation PiZZ1 No No Yes - Homozygous CRISPR-Cas9 editing with DNA oligo repair template