iPSC Lines - Detail

Designation
PiZZ1 MZ
Alias
PiZZ1-1-Cr4-MZ3-7
Description
mono-allelic CRISPR correction of Z mutation
Species Cell Type Disease Ethnicity Race Secondary Race Karyotype Age Parent Avail
Human IPSC Alpha-1 antitrypsin deficiency Not Hisp/Lat White 46XY 44 PiZZ1 Yes


 
Institution Boston University
Passage Number 54
Starting Materials PBMCs
Culture Platform mTeSR adapted
IPSC Reprogramming Method EF1a-hSTEMCCA4 loxp lentiviral infection
 
 
 
 
File Name Document Type
PiZZ1-MZ KT.pdf Karyotype
 
 
Description Parent Reporter Reporter Type Reporter Technique Knockout Gene Correction Other Text
mono-allelic CRISPR correction of Z mutation PiZZ1 No No Yes - Heterozygous CRISPR-Cas9 editing with DNA oligo repair template