Induced Pluripotent Stem Cells (iPSCs) generated by forced overexpression of defined transcription factors in somatic cells hold great promise for human disease research and personalized medicine. iPSCs show extensive self-renewal and have the ability to become any cell type in the body, providing an inexhaustible source of cells for in vitro disease modeling studies, screening of pharmacological compounds and regenerative therapies.
The Center for Regenerative Medicine (CReM) iPSC Core was created to expedite the use of iPSC technology by providing essential services and support to on-campus investigators and the broader scientific community. We will provide all available iPSC lines to the entire academy research community. To achieve this goal the CReM iPSC Core will:
- Generate and characterize iPSC lines from samples of adult tissues provided by the investigator.
- Serve as a repository for sharing control and disease-specific hiPSC lines with internal and external investigators to conduct both basic and translational research.
- Provide expertise, protocols and training to support work involving human iPSCs.
Please visit the Info page for more information.